Cytokine Profiling in Aqueous Humor Samples From Patients With Non-Infectious Uveitis Associated With Systemic Inflammatory Diseases
Identifieur interne : 000448 ( Main/Exploration ); précédent : 000447; suivant : 000449Cytokine Profiling in Aqueous Humor Samples From Patients With Non-Infectious Uveitis Associated With Systemic Inflammatory Diseases
Auteurs : Martina Bonacini [Italie] ; Alessandra Soriano [Italie] ; Luca Cimino [Italie] ; Luca De Simone [Italie] ; Elena Bolletta [Italie] ; Fabrizio Gozzi [Italie] ; Francesco Muratore [Italie] ; Maria Nicastro [Italie] ; Lucia Belloni [Italie] ; Alessandro Zerbini [Italie] ; Luigi Fontana [Italie] ; Carlo Salvarani [Italie] ; Stefania Croci [Italie]Source :
- Frontiers in Immunology [ 1664-3224 ] ; 2020.
Abstract
Non-infectious uveitis are intraocular inflammatory conditions caused by dysregulated activation of the immune response without any detectable infectious agents. The aim of this study was to explore potential markers and therapeutic targets for two distinct types of non-infectious uveitis associated with Behçet's disease (BD) and Vogt Koyanagi Harada (VKH) disease. Concentrations of 27 cytokines were investigated in aqueous humor (AH) samples from patients with active uveitis vs. healthy controls (HC) (
Url:
DOI: 10.3389/fimmu.2020.00358
PubMed: 32210963
PubMed Central: 7077343
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000A64
- to stream Pmc, to step Curation: 000A64
- to stream Pmc, to step Checkpoint: 000306
- to stream Ncbi, to step Merge: 002A37
- to stream Ncbi, to step Curation: 002A37
- to stream Ncbi, to step Checkpoint: 002A37
- to stream Main, to step Merge: 000448
- to stream Main, to step Curation: 000448
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Cytokine Profiling in Aqueous Humor Samples From Patients With Non-Infectious Uveitis Associated With Systemic Inflammatory Diseases</title><author><name sortKey="Bonacini, Martina" sort="Bonacini, Martina" uniqKey="Bonacini M" first="Martina" last="Bonacini">Martina Bonacini</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Clinical Immunology, Allergy and Advanced Biotechnologies Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia</institution>,<addr-line>Reggio Emilia</addr-line>,<country>Italy</country></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Soriano, Alessandra" sort="Soriano, Alessandra" uniqKey="Soriano A" first="Alessandra" last="Soriano">Alessandra Soriano</name><affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Rheumatology Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia</institution>,<addr-line>Reggio Emilia</addr-line>,<country>Italy</country></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Cimino, Luca" sort="Cimino, Luca" uniqKey="Cimino L" first="Luca" last="Cimino">Luca Cimino</name><affiliation wicri:level="1"><nlm:aff id="aff3"><institution>Ocular Immunology Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia</institution>,<addr-line>Reggio Emilia</addr-line>,<country>Italy</country></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="De Simone, Luca" sort="De Simone, Luca" uniqKey="De Simone L" first="Luca" last="De Simone">Luca De Simone</name><affiliation wicri:level="1"><nlm:aff id="aff3"><institution>Ocular Immunology Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia</institution>,<addr-line>Reggio Emilia</addr-line>,<country>Italy</country></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Bolletta, Elena" sort="Bolletta, Elena" uniqKey="Bolletta E" first="Elena" last="Bolletta">Elena Bolletta</name><affiliation wicri:level="1"><nlm:aff id="aff3"><institution>Ocular Immunology Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia</institution>,<addr-line>Reggio Emilia</addr-line>,<country>Italy</country></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Gozzi, Fabrizio" sort="Gozzi, Fabrizio" uniqKey="Gozzi F" first="Fabrizio" last="Gozzi">Fabrizio Gozzi</name><affiliation wicri:level="1"><nlm:aff id="aff3"><institution>Ocular Immunology Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia</institution>,<addr-line>Reggio Emilia</addr-line>,<country>Italy</country></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Muratore, Francesco" sort="Muratore, Francesco" uniqKey="Muratore F" first="Francesco" last="Muratore">Francesco Muratore</name><affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Rheumatology Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia</institution>,<addr-line>Reggio Emilia</addr-line>,<country>Italy</country></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Nicastro, Maria" sort="Nicastro, Maria" uniqKey="Nicastro M" first="Maria" last="Nicastro">Maria Nicastro</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Clinical Immunology, Allergy and Advanced Biotechnologies Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia</institution>,<addr-line>Reggio Emilia</addr-line>,<country>Italy</country></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Belloni, Lucia" sort="Belloni, Lucia" uniqKey="Belloni L" first="Lucia" last="Belloni">Lucia Belloni</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Clinical Immunology, Allergy and Advanced Biotechnologies Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia</institution>,<addr-line>Reggio Emilia</addr-line>,<country>Italy</country></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Zerbini, Alessandro" sort="Zerbini, Alessandro" uniqKey="Zerbini A" first="Alessandro" last="Zerbini">Alessandro Zerbini</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Clinical Immunology, Allergy and Advanced Biotechnologies Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia</institution>,<addr-line>Reggio Emilia</addr-line>,<country>Italy</country></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Fontana, Luigi" sort="Fontana, Luigi" uniqKey="Fontana L" first="Luigi" last="Fontana">Luigi Fontana</name><affiliation wicri:level="1"><nlm:aff id="aff4"><institution>Ophthalmology Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia</institution>,<addr-line>Reggio Emilia</addr-line>,<country>Italy</country></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Salvarani, Carlo" sort="Salvarani, Carlo" uniqKey="Salvarani C" first="Carlo" last="Salvarani">Carlo Salvarani</name><affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Rheumatology Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia</institution>,<addr-line>Reggio Emilia</addr-line>,<country>Italy</country></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff5"><institution>Department of Surgery, Medicine, Dentistry and Morphological Sciences, With Interest in Transplants, Oncology and Regenerative Medicine, University of Modena and Reggio Emilia</institution>,<addr-line>Modena</addr-line>,<country>Italy</country></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Croci, Stefania" sort="Croci, Stefania" uniqKey="Croci S" first="Stefania" last="Croci">Stefania Croci</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Clinical Immunology, Allergy and Advanced Biotechnologies Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia</institution>,<addr-line>Reggio Emilia</addr-line>,<country>Italy</country></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">32210963</idno><idno type="pmc">7077343</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077343</idno><idno type="RBID">PMC:7077343</idno><idno type="doi">10.3389/fimmu.2020.00358</idno><date when="2020">2020</date><idno type="wicri:Area/Pmc/Corpus">000A64</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000A64</idno><idno type="wicri:Area/Pmc/Curation">000A64</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000A64</idno><idno type="wicri:Area/Pmc/Checkpoint">000306</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000306</idno><idno type="wicri:Area/Ncbi/Merge">002A37</idno><idno type="wicri:Area/Ncbi/Curation">002A37</idno><idno type="wicri:Area/Ncbi/Checkpoint">002A37</idno><idno type="wicri:Area/Main/Merge">000448</idno><idno type="wicri:Area/Main/Curation">000448</idno><idno type="wicri:Area/Main/Exploration">000448</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Cytokine Profiling in Aqueous Humor Samples From Patients With Non-Infectious Uveitis Associated With Systemic Inflammatory Diseases</title><author><name sortKey="Bonacini, Martina" sort="Bonacini, Martina" uniqKey="Bonacini M" first="Martina" last="Bonacini">Martina Bonacini</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Clinical Immunology, Allergy and Advanced Biotechnologies Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia</institution>,<addr-line>Reggio Emilia</addr-line>,<country>Italy</country></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Soriano, Alessandra" sort="Soriano, Alessandra" uniqKey="Soriano A" first="Alessandra" last="Soriano">Alessandra Soriano</name><affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Rheumatology Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia</institution>,<addr-line>Reggio Emilia</addr-line>,<country>Italy</country></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Cimino, Luca" sort="Cimino, Luca" uniqKey="Cimino L" first="Luca" last="Cimino">Luca Cimino</name><affiliation wicri:level="1"><nlm:aff id="aff3"><institution>Ocular Immunology Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia</institution>,<addr-line>Reggio Emilia</addr-line>,<country>Italy</country></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="De Simone, Luca" sort="De Simone, Luca" uniqKey="De Simone L" first="Luca" last="De Simone">Luca De Simone</name><affiliation wicri:level="1"><nlm:aff id="aff3"><institution>Ocular Immunology Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia</institution>,<addr-line>Reggio Emilia</addr-line>,<country>Italy</country></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Bolletta, Elena" sort="Bolletta, Elena" uniqKey="Bolletta E" first="Elena" last="Bolletta">Elena Bolletta</name><affiliation wicri:level="1"><nlm:aff id="aff3"><institution>Ocular Immunology Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia</institution>,<addr-line>Reggio Emilia</addr-line>,<country>Italy</country></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Gozzi, Fabrizio" sort="Gozzi, Fabrizio" uniqKey="Gozzi F" first="Fabrizio" last="Gozzi">Fabrizio Gozzi</name><affiliation wicri:level="1"><nlm:aff id="aff3"><institution>Ocular Immunology Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia</institution>,<addr-line>Reggio Emilia</addr-line>,<country>Italy</country></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Muratore, Francesco" sort="Muratore, Francesco" uniqKey="Muratore F" first="Francesco" last="Muratore">Francesco Muratore</name><affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Rheumatology Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia</institution>,<addr-line>Reggio Emilia</addr-line>,<country>Italy</country></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Nicastro, Maria" sort="Nicastro, Maria" uniqKey="Nicastro M" first="Maria" last="Nicastro">Maria Nicastro</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Clinical Immunology, Allergy and Advanced Biotechnologies Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia</institution>,<addr-line>Reggio Emilia</addr-line>,<country>Italy</country></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Belloni, Lucia" sort="Belloni, Lucia" uniqKey="Belloni L" first="Lucia" last="Belloni">Lucia Belloni</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Clinical Immunology, Allergy and Advanced Biotechnologies Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia</institution>,<addr-line>Reggio Emilia</addr-line>,<country>Italy</country></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Zerbini, Alessandro" sort="Zerbini, Alessandro" uniqKey="Zerbini A" first="Alessandro" last="Zerbini">Alessandro Zerbini</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Clinical Immunology, Allergy and Advanced Biotechnologies Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia</institution>,<addr-line>Reggio Emilia</addr-line>,<country>Italy</country></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Fontana, Luigi" sort="Fontana, Luigi" uniqKey="Fontana L" first="Luigi" last="Fontana">Luigi Fontana</name><affiliation wicri:level="1"><nlm:aff id="aff4"><institution>Ophthalmology Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia</institution>,<addr-line>Reggio Emilia</addr-line>,<country>Italy</country></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Salvarani, Carlo" sort="Salvarani, Carlo" uniqKey="Salvarani C" first="Carlo" last="Salvarani">Carlo Salvarani</name><affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Rheumatology Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia</institution>,<addr-line>Reggio Emilia</addr-line>,<country>Italy</country></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff5"><institution>Department of Surgery, Medicine, Dentistry and Morphological Sciences, With Interest in Transplants, Oncology and Regenerative Medicine, University of Modena and Reggio Emilia</institution>,<addr-line>Modena</addr-line>,<country>Italy</country></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Croci, Stefania" sort="Croci, Stefania" uniqKey="Croci S" first="Stefania" last="Croci">Stefania Croci</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Clinical Immunology, Allergy and Advanced Biotechnologies Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia</institution>,<addr-line>Reggio Emilia</addr-line>,<country>Italy</country></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></analytic><series><title level="j">Frontiers in Immunology</title><idno type="eISSN">1664-3224</idno><imprint><date when="2020">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Non-infectious uveitis are intraocular inflammatory conditions caused by dysregulated activation of the immune response without any detectable infectious agents. The aim of this study was to explore potential markers and therapeutic targets for two distinct types of non-infectious uveitis associated with Behçet's disease (BD) and Vogt Koyanagi Harada (VKH) disease. Concentrations of 27 cytokines were investigated in aqueous humor (AH) samples from patients with active uveitis vs. healthy controls (HC) (<italic>n</italic> = 10 patients with BD-associated uveitis; <italic>n</italic> = 10 patients with VKH-associated uveitis; <italic>n</italic> = 10 HC) using the Bio-Plex Pro<sup>TM</sup> human cytokine group I panel. Additionally, leukocytes in AH samples were counted with hemocytometers and characterized by flow cytometry. Eleven cytokines were differentially expressed between patients with uveitis and HC with a median concentration greater than 10 pg/ml. IL-6, IP-10, G-CSF, and IFNγ showed higher concentrations in AH samples from both BD and VKH patients while IL-2, IL-8, IL-13, TNFα, eotaxin, IL-1ra showed statistically significant higher concentrations only in AH samples from BD patients. GM-CSF was the sole cytokine with an opposite profile showing decreased levels in AH samples from BD patients. IL-1ra and IL-6 were detected at higher frequencies in AH samples from BD and VKH patients compared with those from HC while IFNγ and TNFα were not detected in HC. The concentrations of IL-6, IL-8, IP-10, G-CSF, IFNγ, TNFα, eotaxin, IL-1ra positively correlated with the concentrations of leukocytes in AH, suggesting that such cytokines can be produced by immune cells and/or attract and/or promote proliferation and survival of immune cells in these types of uveitis. The correlation matrix of cytokine concentrations in AH samples revealed that IFNγ, TNFα, eotaxin, IL-6, G-CSF highly correlated each other. The ratios of cytokine concentrations between AH and plasma intra-individuals showed that IL-2, IL-6, IP-10, GM-CSF were increased intraocularly. In conclusion, AH sampling followed by multiplex analysis of cytokines should be fostered in non-infectious uveitis to identify cytokines dysregulated intraocularly in each individual laying the groundwork for precision medicine.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Jabs, Da" uniqKey="Jabs D">DA Jabs</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Barisani Asenbauer, T" uniqKey="Barisani Asenbauer T">T Barisani-Asenbauer</name></author><author><name sortKey="Maca, Sm" uniqKey="Maca S">SM Maca</name></author><author><name sortKey="Mejdoubi, L" uniqKey="Mejdoubi L">L Mejdoubi</name></author><author><name sortKey="Emminger, W" uniqKey="Emminger W">W Emminger</name></author><author><name sortKey="Machold, K" uniqKey="Machold K">K Machold</name></author><author><name sortKey="Auer, H" uniqKey="Auer H">H Auer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bertrand, Pj" uniqKey="Bertrand P">PJ Bertrand</name></author><author><name sortKey="Jamilloux, Y" uniqKey="Jamilloux Y">Y Jamilloux</name></author><author><name sortKey="Ecochard, R" uniqKey="Ecochard R">R Ecochard</name></author><author><name sortKey="Richard Colmant, G" uniqKey="Richard Colmant G">G Richard-Colmant</name></author><author><name sortKey="Gerfaud Valentin, M" uniqKey="Gerfaud Valentin M">M Gerfaud-Valentin</name></author><author><name sortKey="Guillaud, M" uniqKey="Guillaud M">M Guillaud</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Prete, M" uniqKey="Prete M">M Prete</name></author><author><name sortKey="Dammacco, R" uniqKey="Dammacco R">R Dammacco</name></author><author><name sortKey="Fatone, Mc" uniqKey="Fatone M">MC Fatone</name></author><author><name sortKey="Racanelli, V" uniqKey="Racanelli V">V Racanelli</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shahab, Ma" uniqKey="Shahab M">MA Shahab</name></author><author><name sortKey="Mir, Ta" uniqKey="Mir T">TA Mir</name></author><author><name sortKey="Zafar, S" uniqKey="Zafar S">S Zafar</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dick, Ad" uniqKey="Dick A">AD Dick</name></author><author><name sortKey="Rosenbaum, Jt" uniqKey="Rosenbaum J">JT Rosenbaum</name></author><author><name sortKey="Al Dhibi, Ha" uniqKey="Al Dhibi H">HA Al-Dhibi</name></author><author><name sortKey="Belfort, R" uniqKey="Belfort R">R Belfort</name></author><author><name sortKey="Brezin, Ap" uniqKey="Brezin A">AP Brezin</name></author><author><name sortKey="Chee, Sp" uniqKey="Chee S">SP Chee</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hatemi, G" uniqKey="Hatemi G">G Hatemi</name></author><author><name sortKey="Christensen, R" uniqKey="Christensen R">R Christensen</name></author><author><name sortKey="Bang, D" uniqKey="Bang D">D Bang</name></author><author><name sortKey="Bodaghi, B" uniqKey="Bodaghi B">B Bodaghi</name></author><author><name sortKey="Celik, Af" uniqKey="Celik A">AF Celik</name></author><author><name sortKey="Fortune, F" uniqKey="Fortune F">F Fortune</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bodaghi, B" uniqKey="Bodaghi B">B Bodaghi</name></author><author><name sortKey="Gendron, G" uniqKey="Gendron G">G Gendron</name></author><author><name sortKey="Wechsler, B" uniqKey="Wechsler B">B Wechsler</name></author><author><name sortKey="Terrada, C" uniqKey="Terrada C">C Terrada</name></author><author><name sortKey="Cassoux, N" uniqKey="Cassoux N">N Cassoux</name></author><author><name sortKey="Huong Du, Lt" uniqKey="Huong Du L">LT Huong du</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hassan, M" uniqKey="Hassan M">M Hassan</name></author><author><name sortKey="Karkhur, S" uniqKey="Karkhur S">S Karkhur</name></author><author><name sortKey="Bae, Jh" uniqKey="Bae J">JH Bae</name></author><author><name sortKey="Halim, Ms" uniqKey="Halim M">MS Halim</name></author><author><name sortKey="Ormaechea, Ms" uniqKey="Ormaechea M">MS Ormaechea</name></author><author><name sortKey="Onghanseng, N" uniqKey="Onghanseng N">N Onghanseng</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Touhami, S" uniqKey="Touhami S">S Touhami</name></author><author><name sortKey="Diwo, E" uniqKey="Diwo E">E Diwo</name></author><author><name sortKey="Seve, P" uniqKey="Seve P">P Seve</name></author><author><name sortKey="Trad, S" uniqKey="Trad S">S Trad</name></author><author><name sortKey="Bielefeld, P" uniqKey="Bielefeld P">P Bielefeld</name></author><author><name sortKey="Sene, D" uniqKey="Sene D">D Sene</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Airody, A" uniqKey="Airody A">A Airody</name></author><author><name sortKey="Heath, G" uniqKey="Heath G">G Heath</name></author><author><name sortKey="Lightman, S" uniqKey="Lightman S">S Lightman</name></author><author><name sortKey="Gale, R" uniqKey="Gale R">R Gale</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Park, Uc" uniqKey="Park U">UC Park</name></author><author><name sortKey="Kim, Tw" uniqKey="Kim T">TW Kim</name></author><author><name sortKey="Yu, Hg" uniqKey="Yu H">HG Yu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Agrawal, R" uniqKey="Agrawal R">R Agrawal</name></author><author><name sortKey="Iyer, J" uniqKey="Iyer J">J Iyer</name></author><author><name sortKey="Connolly, J" uniqKey="Connolly J">J Connolly</name></author><author><name sortKey="Iwata, D" uniqKey="Iwata D">D Iwata</name></author><author><name sortKey="Teoh, S" uniqKey="Teoh S">S Teoh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Davatchi, F" uniqKey="Davatchi F">F Davatchi</name></author><author><name sortKey="Chams Davatchi, C" uniqKey="Chams Davatchi C">C Chams-Davatchi</name></author><author><name sortKey="Shams, H" uniqKey="Shams H">H Shams</name></author><author><name sortKey="Shahram, F" uniqKey="Shahram F">F Shahram</name></author><author><name sortKey="Nadji, A" uniqKey="Nadji A">A Nadji</name></author><author><name sortKey="Akhlaghi, M" uniqKey="Akhlaghi M">M Akhlaghi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lavezzo, Mm" uniqKey="Lavezzo M">MM Lavezzo</name></author><author><name sortKey="Sakata, Vm" uniqKey="Sakata V">VM Sakata</name></author><author><name sortKey="Morita, C" uniqKey="Morita C">C Morita</name></author><author><name sortKey="Rodriguez, Ee" uniqKey="Rodriguez E">EE Rodriguez</name></author><author><name sortKey="Abdallah, Sf" uniqKey="Abdallah S">SF Abdallah</name></author><author><name sortKey="Da Silva, Ft" uniqKey="Da Silva F">FT da Silva</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Read, Rw" uniqKey="Read R">RW Read</name></author><author><name sortKey="Holland, Gn" uniqKey="Holland G">GN Holland</name></author><author><name sortKey="Rao, Na" uniqKey="Rao N">NA Rao</name></author><author><name sortKey="Tabbara, Kf" uniqKey="Tabbara K">KF Tabbara</name></author><author><name sortKey="Ohno, S" uniqKey="Ohno S">S Ohno</name></author><author><name sortKey="Arellanes Garcia, L" uniqKey="Arellanes Garcia L">L Arellanes-Garcia</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cimino, L" uniqKey="Cimino L">L Cimino</name></author><author><name sortKey="Aldigeri, R" uniqKey="Aldigeri R">R Aldigeri</name></author><author><name sortKey="Parmeggiani, M" uniqKey="Parmeggiani M">M Parmeggiani</name></author><author><name sortKey="Belloni, L" uniqKey="Belloni L">L Belloni</name></author><author><name sortKey="Zotti, Ca" uniqKey="Zotti C">CA Zotti</name></author><author><name sortKey="Fontana, L" uniqKey="Fontana L">L Fontana</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Metsalu, T" uniqKey="Metsalu T">T Metsalu</name></author><author><name sortKey="Vilo, J" uniqKey="Vilo J">J Vilo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="El Asrar, Am" uniqKey="El Asrar A">AM El-Asrar</name></author><author><name sortKey="Struyf, S" uniqKey="Struyf S">S Struyf</name></author><author><name sortKey="Kangave, D" uniqKey="Kangave D">D Kangave</name></author><author><name sortKey="Al Obeidan, Ss" uniqKey="Al Obeidan S">SS Al-Obeidan</name></author><author><name sortKey="Opdenakker, G" uniqKey="Opdenakker G">G Opdenakker</name></author><author><name sortKey="Geboes, K" uniqKey="Geboes K">K Geboes</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="El Asrar, Am" uniqKey="El Asrar A">AM El-Asrar</name></author><author><name sortKey="Al Obeidan, Ss" uniqKey="Al Obeidan S">SS Al-Obeidan</name></author><author><name sortKey="Kangave, D" uniqKey="Kangave D">D Kangave</name></author><author><name sortKey="Geboes, K" uniqKey="Geboes K">K Geboes</name></author><author><name sortKey="Opdenakker, G" uniqKey="Opdenakker G">G Opdenakker</name></author><author><name sortKey="Van, Dj" uniqKey="Van D">DJ Van</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Abu, El Asrar Am" uniqKey="Abu E">El-Asrar AM Abu</name></author><author><name sortKey="Berghmans, N" uniqKey="Berghmans N">N Berghmans</name></author><author><name sortKey="Al Obeidan, Sa" uniqKey="Al Obeidan S">SA Al-Obeidan</name></author><author><name sortKey="Mousa, A" uniqKey="Mousa A">A Mousa</name></author><author><name sortKey="Opdenakker, G" uniqKey="Opdenakker G">G Opdenakker</name></author><author><name sortKey="Van, Dj" uniqKey="Van D">DJ Van</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Abu, El Asrar Am" uniqKey="Abu E">El-Asrar AM Abu</name></author><author><name sortKey="Berghmans, N" uniqKey="Berghmans N">N Berghmans</name></author><author><name sortKey="Al Obeidan, Sa" uniqKey="Al Obeidan S">SA Al-Obeidan</name></author><author><name sortKey="Gikandi, Pw" uniqKey="Gikandi P">PW Gikandi</name></author><author><name sortKey="Opdenakker, G" uniqKey="Opdenakker G">G Opdenakker</name></author><author><name sortKey="Van, Dj" uniqKey="Van D">DJ Van</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bhattacharya, P" uniqKey="Bhattacharya P">P Bhattacharya</name></author><author><name sortKey="Thiruppathi, M" uniqKey="Thiruppathi M">M Thiruppathi</name></author><author><name sortKey="Elshabrawy, Ha" uniqKey="Elshabrawy H">HA Elshabrawy</name></author><author><name sortKey="Alharshawi, K" uniqKey="Alharshawi K">K Alharshawi</name></author><author><name sortKey="Kumar, P" uniqKey="Kumar P">P Kumar</name></author><author><name sortKey="Prabhakar, Bs" uniqKey="Prabhakar B">BS Prabhakar</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bhattacharya, P" uniqKey="Bhattacharya P">P Bhattacharya</name></author><author><name sortKey="Budnick, I" uniqKey="Budnick I">I Budnick</name></author><author><name sortKey="Singh, M" uniqKey="Singh M">M Singh</name></author><author><name sortKey="Thiruppathi, M" uniqKey="Thiruppathi M">M Thiruppathi</name></author><author><name sortKey="Alharshawi, K" uniqKey="Alharshawi K">K Alharshawi</name></author><author><name sortKey="Elshabrawy, H" uniqKey="Elshabrawy H">H Elshabrawy</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, Tt" uniqKey="Wang T">TT Wang</name></author><author><name sortKey="Zhao, Yl" uniqKey="Zhao Y">YL Zhao</name></author><author><name sortKey="Peng, Ls" uniqKey="Peng L">LS Peng</name></author><author><name sortKey="Chen, N" uniqKey="Chen N">N Chen</name></author><author><name sortKey="Chen, W" uniqKey="Chen W">W Chen</name></author><author><name sortKey="Lv, Yp" uniqKey="Lv Y">YP Lv</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Taylor, Aw" uniqKey="Taylor A">AW Taylor</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fabiani, C" uniqKey="Fabiani C">C Fabiani</name></author><author><name sortKey="Vitale, A" uniqKey="Vitale A">A Vitale</name></author><author><name sortKey="Lopalco, G" uniqKey="Lopalco G">G Lopalco</name></author><author><name sortKey="Iannone, F" uniqKey="Iannone F">F Iannone</name></author><author><name sortKey="Frediani, B" uniqKey="Frediani B">B Frediani</name></author><author><name sortKey="Cantarini, L" uniqKey="Cantarini L">L Cantarini</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fabiani, C" uniqKey="Fabiani C">C Fabiani</name></author><author><name sortKey="Vitale, A" uniqKey="Vitale A">A Vitale</name></author><author><name sortKey="Emmi, G" uniqKey="Emmi G">G Emmi</name></author><author><name sortKey="Vannozzi, L" uniqKey="Vannozzi L">L Vannozzi</name></author><author><name sortKey="Lopalco, G" uniqKey="Lopalco G">G Lopalco</name></author><author><name sortKey="Guerriero, S" uniqKey="Guerriero S">S Guerriero</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schwartzman, S" uniqKey="Schwartzman S">S Schwartzman</name></author><author><name sortKey="Schwartzman, M" uniqKey="Schwartzman M">M Schwartzman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Niccoli, L" uniqKey="Niccoli L">L Niccoli</name></author><author><name sortKey="Nannini, C" uniqKey="Nannini C">C Nannini</name></author><author><name sortKey="Benucci, M" uniqKey="Benucci M">M Benucci</name></author><author><name sortKey="Chindamo, D" uniqKey="Chindamo D">D Chindamo</name></author><author><name sortKey="Cassara, E" uniqKey="Cassara E">E Cassara</name></author><author><name sortKey="Salvarani, C" uniqKey="Salvarani C">C Salvarani</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fabiani, C" uniqKey="Fabiani C">C Fabiani</name></author><author><name sortKey="Vitale, A" uniqKey="Vitale A">A Vitale</name></author><author><name sortKey="Rigante, D" uniqKey="Rigante D">D Rigante</name></author><author><name sortKey="Emmi, G" uniqKey="Emmi G">G Emmi</name></author><author><name sortKey="Bitossi, A" uniqKey="Bitossi A">A Bitossi</name></author><author><name sortKey="Lopalco, G" uniqKey="Lopalco G">G Lopalco</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Eser Ozturk, H" uniqKey="Eser Ozturk H">H Eser-Ozturk</name></author><author><name sortKey="Sullu, Y" uniqKey="Sullu Y">Y Sullu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hasanreisoglu, M" uniqKey="Hasanreisoglu M">M Hasanreisoglu</name></author><author><name sortKey="Cubuk, Mo" uniqKey="Cubuk M">MO Cubuk</name></author><author><name sortKey="Ozdek, S" uniqKey="Ozdek S">S Ozdek</name></author><author><name sortKey="Gurelik, G" uniqKey="Gurelik G">G Gurelik</name></author><author><name sortKey="Aktas, Z" uniqKey="Aktas Z">Z Aktas</name></author><author><name sortKey="Hasanreisoglu, B" uniqKey="Hasanreisoglu B">B Hasanreisoglu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Leccese, P" uniqKey="Leccese P">P Leccese</name></author><author><name sortKey="Alpsoy, E" uniqKey="Alpsoy E">E Alpsoy</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Albayrak, O" uniqKey="Albayrak O">O Albayrak</name></author><author><name sortKey="Oray, M" uniqKey="Oray M">M Oray</name></author><author><name sortKey="Can, F" uniqKey="Can F">F Can</name></author><author><name sortKey="Uludag, Kg" uniqKey="Uludag K">KG Uludag</name></author><author><name sortKey="Gul, A" uniqKey="Gul A">A Gul</name></author><author><name sortKey="Tugal Tutkun, I" uniqKey="Tugal Tutkun I">I Tugal-Tutkun</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Aydinoglu Candan, O" uniqKey="Aydinoglu Candan O">O Aydinoglu-Candan</name></author><author><name sortKey="Araz Ersan, B" uniqKey="Araz Ersan B">B Araz-Ersan</name></author><author><name sortKey="Gul, A" uniqKey="Gul A">A Gul</name></author><author><name sortKey="Badur, S" uniqKey="Badur S">S Badur</name></author><author><name sortKey="Tugal Tutkun, I" uniqKey="Tugal Tutkun I">I Tugal-Tutkun</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Treusch, M" uniqKey="Treusch M">M Treusch</name></author><author><name sortKey="Vonthein, R" uniqKey="Vonthein R">R Vonthein</name></author><author><name sortKey="Baur, M" uniqKey="Baur M">M Baur</name></author><author><name sortKey="Gunaydin, I" uniqKey="Gunaydin I">I Gunaydin</name></author><author><name sortKey="Koch, S" uniqKey="Koch S">S Koch</name></author><author><name sortKey="Stubiger, N" uniqKey="Stubiger N">N Stubiger</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gillies, Mc" uniqKey="Gillies M">MC Gillies</name></author><author><name sortKey="Su, T" uniqKey="Su T">T Su</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Thomas, As" uniqKey="Thomas A">AS Thomas</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sepah, Yj" uniqKey="Sepah Y">YJ Sepah</name></author><author><name sortKey="Sadiq, Ma" uniqKey="Sadiq M">MA Sadiq</name></author><author><name sortKey="Chu, Ds" uniqKey="Chu D">DS Chu</name></author><author><name sortKey="Dacey, M" uniqKey="Dacey M">M Dacey</name></author><author><name sortKey="Gallemore, R" uniqKey="Gallemore R">R Gallemore</name></author><author><name sortKey="Dayani, P" uniqKey="Dayani P">P Dayani</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lopalco, G" uniqKey="Lopalco G">G Lopalco</name></author><author><name sortKey="Fabiani, C" uniqKey="Fabiani C">C Fabiani</name></author><author><name sortKey="Sota, J" uniqKey="Sota J">J Sota</name></author><author><name sortKey="Lucherini, Om" uniqKey="Lucherini O">OM Lucherini</name></author><author><name sortKey="Tosi, Gm" uniqKey="Tosi G">GM Tosi</name></author><author><name sortKey="Frediani, B" uniqKey="Frediani B">B Frediani</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhao, B" uniqKey="Zhao B">B Zhao</name></author><author><name sortKey="Chen, W" uniqKey="Chen W">W Chen</name></author><author><name sortKey="Jiang, R" uniqKey="Jiang R">R Jiang</name></author><author><name sortKey="Zhang, R" uniqKey="Zhang R">R Zhang</name></author><author><name sortKey="Wang, Y" uniqKey="Wang Y">Y Wang</name></author><author><name sortKey="Wang, L" uniqKey="Wang L">L Wang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fabiani, C" uniqKey="Fabiani C">C Fabiani</name></author><author><name sortKey="Vitale, A" uniqKey="Vitale A">A Vitale</name></author><author><name sortKey="Emmi, G" uniqKey="Emmi G">G Emmi</name></author><author><name sortKey="Lopalco, G" uniqKey="Lopalco G">G Lopalco</name></author><author><name sortKey="Vannozzi, L" uniqKey="Vannozzi L">L Vannozzi</name></author><author><name sortKey="Guerriero, S" uniqKey="Guerriero S">S Guerriero</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Priya, Cg" uniqKey="Priya C">CG Priya</name></author><author><name sortKey="Rathinam, Sr" uniqKey="Rathinam S">SR Rathinam</name></author><author><name sortKey="Muthukkaruppan, V" uniqKey="Muthukkaruppan V">V Muthukkaruppan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Curnow, Sj" uniqKey="Curnow S">SJ Curnow</name></author><author><name sortKey="Falciani, F" uniqKey="Falciani F">F Falciani</name></author><author><name sortKey="Durrani, Om" uniqKey="Durrani O">OM Durrani</name></author><author><name sortKey="Cheung, Cm" uniqKey="Cheung C">CM Cheung</name></author><author><name sortKey="Ross, Ej" uniqKey="Ross E">EJ Ross</name></author><author><name sortKey="Wloka, K" uniqKey="Wloka K">K Wloka</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Abu, El Asrar Am" uniqKey="Abu E">El-Asrar AM Abu</name></author><author><name sortKey="Berghmans, N" uniqKey="Berghmans N">N Berghmans</name></author><author><name sortKey="Al Obeidan, Sa" uniqKey="Al Obeidan S">SA Al-Obeidan</name></author><author><name sortKey="Gikandi, Pw" uniqKey="Gikandi P">PW Gikandi</name></author><author><name sortKey="Opdenakker, G" uniqKey="Opdenakker G">G Opdenakker</name></author><author><name sortKey="Van, Dj" uniqKey="Van D">DJ Van</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ahn, Jk" uniqKey="Ahn J">JK Ahn</name></author><author><name sortKey="Yu, Hg" uniqKey="Yu H">HG Yu</name></author><author><name sortKey="Chung, H" uniqKey="Chung H">H Chung</name></author><author><name sortKey="Park, Yg" uniqKey="Park Y">YG Park</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Takase, H" uniqKey="Takase H">H Takase</name></author><author><name sortKey="Futagami, Y" uniqKey="Futagami Y">Y Futagami</name></author><author><name sortKey="Yoshida, T" uniqKey="Yoshida T">T Yoshida</name></author><author><name sortKey="Kamoi, K" uniqKey="Kamoi K">K Kamoi</name></author><author><name sortKey="Sugita, S" uniqKey="Sugita S">S Sugita</name></author><author><name sortKey="Imai, Y" uniqKey="Imai Y">Y Imai</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lacomba, Ms" uniqKey="Lacomba M">MS Lacomba</name></author><author><name sortKey="Martin, Cm" uniqKey="Martin C">CM Martin</name></author><author><name sortKey="Chamond, Rr" uniqKey="Chamond R">RR Chamond</name></author><author><name sortKey="Galera, Jm" uniqKey="Galera J">JM Galera</name></author><author><name sortKey="Omar, M" uniqKey="Omar M">M Omar</name></author><author><name sortKey="Estevez, Ec" uniqKey="Estevez E">EC Estevez</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bae, Jh" uniqKey="Bae J">JH Bae</name></author><author><name sortKey="Lee, Sc" uniqKey="Lee S">SC Lee</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Simsek, M" uniqKey="Simsek M">M Simsek</name></author><author><name sortKey="Cakar, Op" uniqKey="Cakar O">OP Cakar</name></author><author><name sortKey="Akbiyik, F" uniqKey="Akbiyik F">F Akbiyik</name></author><author><name sortKey="Citirik, M" uniqKey="Citirik M">M Citirik</name></author><author><name sortKey="Berker, N" uniqKey="Berker N">N Berker</name></author><author><name sortKey="Ozdamar, Ey" uniqKey="Ozdamar E">EY Ozdamar</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pei, M" uniqKey="Pei M">M Pei</name></author><author><name sortKey="Liu, X" uniqKey="Liu X">X Liu</name></author><author><name sortKey="Zhao, C" uniqKey="Zhao C">C Zhao</name></author><author><name sortKey="Gao, F" uniqKey="Gao F">F Gao</name></author><author><name sortKey="Tao, Y" uniqKey="Tao Y">Y Tao</name></author><author><name sortKey="Zhang, M" uniqKey="Zhang M">M Zhang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="El Asrar, Ama" uniqKey="El Asrar A">AMA El-Asrar</name></author><author><name sortKey="Berghmans, N" uniqKey="Berghmans N">N Berghmans</name></author><author><name sortKey="Al Obeidan, Sa" uniqKey="Al Obeidan S">SA Al-Obeidan</name></author><author><name sortKey="Gikandi, Pw" uniqKey="Gikandi P">PW Gikandi</name></author><author><name sortKey="Opdenakker, G" uniqKey="Opdenakker G">G Opdenakker</name></author><author><name sortKey="Van, Dj" uniqKey="Van D">DJ Van</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kim, Tw" uniqKey="Kim T">TW Kim</name></author><author><name sortKey="Chung, H" uniqKey="Chung H">H Chung</name></author><author><name sortKey="Yu, Hg" uniqKey="Yu H">HG Yu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Paroli, Mp" uniqKey="Paroli M">MP Paroli</name></author><author><name sortKey="Teodori, C" uniqKey="Teodori C">C Teodori</name></author><author><name sortKey="D Alessandro, M" uniqKey="D Alessandro M">M D'Alessandro</name></author><author><name sortKey="Mariani, P" uniqKey="Mariani P">P Mariani</name></author><author><name sortKey="Iannucci, G" uniqKey="Iannucci G">G Iannucci</name></author><author><name sortKey="Paroli, M" uniqKey="Paroli M">M Paroli</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="El Asrar, Am" uniqKey="El Asrar A">AM El-Asrar</name></author><author><name sortKey="Berghmans, N" uniqKey="Berghmans N">N Berghmans</name></author><author><name sortKey="Al Obeidan, Sa" uniqKey="Al Obeidan S">SA Al-Obeidan</name></author><author><name sortKey="Gikandi, Pw" uniqKey="Gikandi P">PW Gikandi</name></author><author><name sortKey="Opdenakker, G" uniqKey="Opdenakker G">G Opdenakker</name></author><author><name sortKey="Van, Dj" uniqKey="Van D">DJ Van</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Italie</li></country></list><tree><country name="Italie"><noRegion><name sortKey="Bonacini, Martina" sort="Bonacini, Martina" uniqKey="Bonacini M" first="Martina" last="Bonacini">Martina Bonacini</name></noRegion><name sortKey="Belloni, Lucia" sort="Belloni, Lucia" uniqKey="Belloni L" first="Lucia" last="Belloni">Lucia Belloni</name><name sortKey="Bolletta, Elena" sort="Bolletta, Elena" uniqKey="Bolletta E" first="Elena" last="Bolletta">Elena Bolletta</name><name sortKey="Cimino, Luca" sort="Cimino, Luca" uniqKey="Cimino L" first="Luca" last="Cimino">Luca Cimino</name><name sortKey="Croci, Stefania" sort="Croci, Stefania" uniqKey="Croci S" first="Stefania" last="Croci">Stefania Croci</name><name sortKey="De Simone, Luca" sort="De Simone, Luca" uniqKey="De Simone L" first="Luca" last="De Simone">Luca De Simone</name><name sortKey="Fontana, Luigi" sort="Fontana, Luigi" uniqKey="Fontana L" first="Luigi" last="Fontana">Luigi Fontana</name><name sortKey="Gozzi, Fabrizio" sort="Gozzi, Fabrizio" uniqKey="Gozzi F" first="Fabrizio" last="Gozzi">Fabrizio Gozzi</name><name sortKey="Muratore, Francesco" sort="Muratore, Francesco" uniqKey="Muratore F" first="Francesco" last="Muratore">Francesco Muratore</name><name sortKey="Nicastro, Maria" sort="Nicastro, Maria" uniqKey="Nicastro M" first="Maria" last="Nicastro">Maria Nicastro</name><name sortKey="Salvarani, Carlo" sort="Salvarani, Carlo" uniqKey="Salvarani C" first="Carlo" last="Salvarani">Carlo Salvarani</name><name sortKey="Salvarani, Carlo" sort="Salvarani, Carlo" uniqKey="Salvarani C" first="Carlo" last="Salvarani">Carlo Salvarani</name><name sortKey="Soriano, Alessandra" sort="Soriano, Alessandra" uniqKey="Soriano A" first="Alessandra" last="Soriano">Alessandra Soriano</name><name sortKey="Zerbini, Alessandro" sort="Zerbini, Alessandro" uniqKey="Zerbini A" first="Alessandro" last="Zerbini">Alessandro Zerbini</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/TocilizumabV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000448 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000448 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= TocilizumabV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:7077343
|texte= Cytokine Profiling in Aqueous Humor Samples From Patients With Non-Infectious Uveitis Associated With Systemic Inflammatory Diseases
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:32210963" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a TocilizumabV1
| This area was generated with Dilib version V0.6.34. |  |